Quick help I need to catch my zzzz’s

How would have John C Calhoun MOST LIKELY responded if the federal government enacted a law banning slavery in
the entire United States in the 1830s?
A)
He would have argued that Southern states would have to follow the law
unless they seceded from the United States.
B)
He would have argued that the law would only apply in states whose
congressional representatives supported the law.
C)
He would have argued that the law was unconstitutional because the
Constitution specifically denied Congress the right to restrict slavery.
D)
He would have argued that Southern states had the right to nullify the law
and residents could practice slavery unless state laws outlawed it.